What percentage of collagen does the Extracellular Matrix primarily consist of?

The Extracellular Matrix (ECM) is crucial for providing structural and biochemical support to surrounding cells. It consists of a variety of proteins, among which collagen is the predominant component. Collagen fibers impart strength and structural integrity to the ECM, making it resilient to mechanical stresses.

In a typical ECM composition, collagen constitutes around 75% of the total protein content. This high percentage highlights the significance of collagen in maintaining the overall architecture and functionality of tissues. The sheer amount of collagen is essential for wound healing, tissue repair, and physiological maintenance throughout various organs and systems in the body.

Given this understanding, the choice reflecting that collagen makes up 75% of the Extracellular Matrix accurately represents the biological reality, emphasizing collagen's role as a foundational protein within the ECM.